Description
SS-31, also known as elamipretide, is a small synthetic peptide designed to concentrate in the inner mitochondrial membrane. Each vial contains 10mg of lyophilized SS-31 for laboratory research.
What Is SS-31?
SS-31 is a four-amino-acid peptide (D-Arg-Dmt-Lys-Phe-NH2) from the Szeto-Schiller family of mitochondria-targeted compounds. Its alternating aromatic and positively charged residues let it cross cell membranes and accumulate at the inner mitochondrial membrane.
There it associates with cardiolipin, a phospholipid that anchors the electron transport chain and supports the folded structure of the mitochondrial cristae. Research models have used SS-31 to study electron transport efficiency, reactive oxygen species production, and mitochondrial structure in cardiac, skeletal-muscle, renal, and aging tissue.
Areas of Research Interest
- Cardiolipin binding and inner-membrane structure
- Electron transport chain efficiency
- Reactive oxygen species and oxidative-stress models
- Cardiac and skeletal-muscle mitochondrial research
- Age-related mitochondrial dysfunction models
Product Specifications
- Compound: SS-31 (elamipretide)
- Contents: 10mg per vial
- Form: Lyophilized powder
- Intended use: Laboratory research only
Handling & Storage
Supplied as a lyophilized (freeze-dried) powder in a sealed vial. Store according to the label, protected from heat, light and moisture.
Frequently Asked Questions
What is cardiolipin, and why does SS-31 target it?
Cardiolipin is a phospholipid found almost exclusively in the inner mitochondrial membrane, where it stabilizes the protein complexes of the electron transport chain. SS-31 associates with cardiolipin rather than binding a receptor, which is an unusual mechanism among research peptides.
Is SS-31 the same as elamipretide?
They refer to the same tetrapeptide sequence. SS-31 is the original research designation; elamipretide is the name used in later development literature.
What does mitochondria-targeted mean?
SS-31’s structure lets it pass through cell membranes and concentrate at the inner mitochondrial membrane, rather than spreading evenly throughout the cell.
What compounds are often studied alongside SS-31?
Mitochondrial research frequently pairs it with MOTS-c and NAD+.
Is SS-31 10mg Vial intended for human use?
No. This product is sold strictly for in vitro and laboratory research by qualified professionals. It is not for human or veterinary use.
Related Research Compounds
Sold for research purposes only. Not intended for human consumption. These statements have not been evaluated by the FDA. This product is not a drug, food, or cosmetic and is not intended to diagnose, treat, cure, or prevent any disease.
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