Description
Melanotan 2 (MT-2) is a synthetic, cyclic analog of alpha-melanocyte-stimulating hormone (alpha-MSH). Each vial contains 10mg of lyophilized Melanotan 2 for laboratory research.
What Is Melanotan 2?
Alpha-MSH is a naturally occurring peptide hormone that regulates melanin production and several central signaling pathways through the melanocortin receptor family. Melanotan 2 is a shortened, cyclized version, a lactam-bridged heptapeptide, engineered to resist enzymatic breakdown.
MT-2 is a non-selective melanocortin agonist with activity at MC1R, MC3R, MC4R, and MC5R. MC1R is associated with melanogenesis in melanocytes, while MC3R and MC4R are studied in the hypothalamus for their roles in energy balance and behavior. This broad receptor profile makes it a useful tool for comparing melanocortin receptor subtypes.
Areas of Research Interest
- MC1R activation and melanogenesis in melanocyte models
- Pigmentation pathway research
- Hypothalamic MC4R signaling
- Melanocortin receptor subtype comparison
- Comparative studies with PT-141
Product Specifications
- Compound: Melanotan 2 (MT-2, cyclic alpha-MSH analog)
- Contents: 10mg per vial
- Form: Lyophilized powder
- Intended use: Laboratory research only
Handling & Storage
Supplied as a lyophilized (freeze-dried) powder in a sealed vial. Store according to the label, protected from heat, light and moisture.
Frequently Asked Questions
How does Melanotan 2 differ from alpha-MSH?
Alpha-MSH is a 13-amino-acid linear peptide that degrades quickly. Melanotan 2 is a cyclic seven-amino-acid analog, and the cyclization confers considerably greater stability. Their receptor affinity profiles also differ.
What does non-selective mean for research design?
Melanotan 2 shows activity at MC1R, MC3R, MC4R and MC5R. Researchers isolating MC1R and pigmentation therefore need controls for activity at the other receptors, which is why MC3R and MC4R-focused work often uses a different analog.
What is the difference between Melanotan 2 and PT-141?
PT-141 is a metabolite of Melanotan 2 that acts mainly at MC3/MC4 receptors. Melanotan 2 acts more broadly, including at MC1R, which is linked to pigmentation.
How is Melanotan 2 supplied?
As a lyophilized powder in a sealed 10mg vial.
Is Melanotan 2 10mg Vial intended for human use?
No. This product is sold strictly for in vitro and laboratory research by qualified professionals. It is not for human or veterinary use.
Related Research Compounds
Sold for research purposes only. Not intended for human consumption. These statements have not been evaluated by the FDA. This product is not a drug, food, or cosmetic and is not intended to diagnose, treat, cure, or prevent any disease.
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