Description
PT-141, also known as bremelanotide, is a synthetic cyclic peptide that acts at melanocortin receptors in the central nervous system. Each vial contains 10mg of lyophilized PT-141 for laboratory research.
What Is PT-141?
PT-141 is a cyclic heptapeptide and an active metabolite of Melanotan 2. Structurally, it lacks the C-terminal amide of its parent compound. It acts mainly at the MC3 and MC4 melanocortin receptors, which are concentrated in the hypothalamus and related brain regions.
Unlike compounds that act on the vascular system, PT-141 is studied for its effects on central neural pathways. Published research has used it to study how melanocortin signaling in the brain influences sexual-motivation behavior in animal models.
Areas of Research Interest
- MC3R and MC4R melanocortin receptor signaling
- Hypothalamic and CNS pathway research
- Sexual-motivation behavior in animal models
- Comparative studies with Melanotan 2
- Combination research with oxytocin
Product Specifications
- Compound: PT-141 (bremelanotide)
- Contents: 10mg per vial
- Form: Lyophilized powder
- Intended use: Laboratory research only
Handling & Storage
Supplied as a lyophilized (freeze-dried) powder in a sealed vial. Store according to the label, protected from heat, light and moisture.
Frequently Asked Questions
What does bremelanotide refer to?
Bremelanotide is the non-proprietary name for the same compound as PT-141. The two are used interchangeably in the literature, with PT-141 being the original research designation.
Which receptors does PT-141 act on?
Published work focuses on MC3R and MC4R, both expressed in the central nervous system. Its reduced MC1R activity relative to other melanocortin analogs is what allows central signaling to be examined with less pigmentation-pathway interference.
How is PT-141 related to Melanotan 2?
PT-141 is a metabolite of Melanotan 2. It is more focused on MC3/MC4 receptors, while Melanotan 2 also acts strongly at MC1R, which is linked to pigmentation.
Is PT-141 available in another format?
Yes. It is also offered pre-mixed with oxytocin in our PT-141 + Oxytocin nasal spray.
Is PT-141 10mg Vial intended for human use?
No. This product is sold strictly for in vitro and laboratory research by qualified professionals. It is not for human or veterinary use.
Related Research Compounds
Sold for research purposes only. Not intended for human consumption. These statements have not been evaluated by the FDA. This product is not a drug, food, or cosmetic and is not intended to diagnose, treat, cure, or prevent any disease.
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