Description
This nasal spray combines Selank and Semax, two synthetic heptapeptides studied almost exclusively through intranasal administration. Each bottle supplies 10mg of each peptide, pre-mixed, which removes the reconstitution step and the dosing variability that comes with it.
Both are short, stabilized analogs of endogenous human sequences — Selank derived from the immunomodulatory tetrapeptide tuftsin, Semax from the ACTH(4–10) fragment — and both carry a C-terminal Pro-Gly-Pro extension that slows enzymatic degradation. Because they act on largely separate pathways, they are frequently run together in comparative neuropeptide work, which is what this pre-mixed format is built for.
What Is Selank + Semax Spray?
Selank is a synthetic analog of tuftsin, a naturally occurring four-amino-acid immunomodulatory peptide (Thr-Lys-Pro-Arg), extended with a Pro-Gly-Pro sequence for stability. Published research has examined its relationship to GABAergic signaling, monoamine systems, and gene expression related to stress-response behavior in animal models.
Semax is a synthetic analog of the ACTH(4–10) fragment, also stabilized with a C-terminal Pro-Gly-Pro. It has no hormonal ACTH activity, and rodent research has focused on BDNF expression, neurotrophic signaling, and cognition-related behavior. Both peptides were developed for intranasal delivery, which is why they are supplied in this format.
Areas of Research Interest
- Neuropeptide and neurotrophic (BDNF) signaling
- GABAergic and monoamine pathway studies
- Stress-response behavior in animal models
- Cognition-related behavioral research
- Intranasal peptide delivery research
Product Specifications
- Compound: Selank + Semax
- Contents: 10mg Selank / 10mg Semax per bottle
- Form: Pre-mixed nasal spray
- Intended use: Laboratory research only
Handling & Storage
Supplied pre-mixed in a sealed spray bottle. Store according to the label, away from heat and direct light.
Frequently Asked Questions
How do Selank and Semax differ in mechanism?
Semax research centers on neurotrophic signaling, particularly BDNF and NGF expression in neuronal culture and rodent models. Selank research centers on GABAergic and monoamine pathways and on the enzymatic breakdown of enkephalins. The two are studied together because those mechanisms are largely independent of one another.
Why does the Pro-Gly-Pro sequence matter?
Native tuftsin and ACTH(4–10) are cleaved rapidly by peptidases. The C-terminal Pro-Gly-Pro extension on both compounds slows that cleavage, which is what makes intranasal delivery practical in a research setting and is itself a common variable in peptide stability studies.
Why is this supplied as a nasal spray?
Selank and Semax were both developed and studied mainly through intranasal delivery, so a pre-mixed spray matches how the published literature approaches them.
What other compounds are used in cognition research?
NAD+ and MOTS-c are often studied in related cellular-energy and aging research.
Is Selank + Semax Spray (10mg/10mg) intended for human use?
No. This product is sold strictly for in vitro and laboratory research by qualified professionals. It is not for human or veterinary use.
Related Research Compounds
Sold for research purposes only. Not intended for human consumption. These statements have not been evaluated by the FDA. This product is not a drug, food, or cosmetic and is not intended to diagnose, treat, cure, or prevent any disease.
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