Description
TB-500 is a synthetic research peptide modeled on thymosin beta-4 (Tβ4), a naturally occurring protein found in most animal cells. Each vial contains 10mg of lyophilized TB-500 for laboratory use.
What Is TB-500?
Thymosin beta-4 is a 43-amino-acid protein and one of the main regulators of G-actin, the building block of the actin cytoskeleton that cells use to change shape and move. By binding and sequestering actin monomers, Tβ4 influences how cells migrate, which is central to how tissue responds to injury.
TB-500 is the name commonly used for synthetic peptides based on the active region of Tβ4. Published research on thymosin beta-4 includes wound-closure, corneal, cardiac, and skeletal-muscle models in animals, along with work on angiogenesis and inflammatory signaling.
Areas of Research Interest
- Actin regulation and cell-migration studies
- Dermal and corneal wound-closure models
- Cardiac and skeletal-muscle tissue models in animals
- Angiogenesis and endothelial cell research
- Combination studies with BPC-157
Product Specifications
- Compound: TB-500 (synthetic thymosin beta-4 peptide)
- Contents: 10mg per vial
- Form: Lyophilized powder
- Intended use: Laboratory research only
Handling & Storage
Supplied as a lyophilized (freeze-dried) powder in a sealed vial. Store according to the label, protected from heat, light and moisture.
Frequently Asked Questions
Why do published studies use a fragment rather than full thymosin beta-4?
The fragment covers the region associated with actin binding, which is the mechanism most of the literature examines. Working with a short synthetic sequence also removes the folding and stability variables that come with a full-length 43-amino-acid protein.
What is the actin-binding domain and why does it matter?
Thymosin beta-4 binds monomeric G-actin, governing how much is available to polymerize into filaments. That balance controls cell motility, which is why actin regulation sits at the center of most TB-500 research.
Is TB-500 the same as thymosin beta-4?
Not exactly. Thymosin beta-4 is the full 43-amino-acid protein. TB-500 refers to synthetic peptides based on its active actin-binding region, which is what is supplied here.
Why do researchers pair TB-500 with BPC-157?
The two compounds are studied through different mechanisms, so labs often compare or combine them. See BPC-157 10mg Vial or the pre-blended BPC-157/TB-500 vial.
Is TB-500 10mg Vial intended for human use?
No. This product is sold strictly for in vitro and laboratory research by qualified professionals. It is not for human or veterinary use.
Related Research Compounds
Sold for research purposes only. Not intended for human consumption. These statements have not been evaluated by the FDA. This product is not a drug, food, or cosmetic and is not intended to diagnose, treat, cure, or prevent any disease.
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