Research Guide · Tissue Repair
BPC-157
BPC-157 is a 15-amino-acid synthetic peptide and one of the most studied compounds in preclinical tissue-repair research. Here is what it is, what the published research has actually looked at, and where the evidence stops.
BPC-157 is supplied as a freeze-dried vial alongside the rest of our lyophilized research peptides.
← All research guidesWhat BPC-157 is
BPC stands for "Body Protection Compound." BPC-157 is a pentadecapeptide, a chain of 15 amino acids, whose sequence was derived from a larger protein isolated from gastric juice. Most of the foundational research comes from Predrag Sikiric's group at the University of Zagreb, which has published on it since the early 1990s.
One property that drew early interest is stability: unlike many short peptides, BPC-157 was reported to remain stable in gastric juice, which is unusual and shaped how it was studied in gut models.
What the research has examined
The published literature on BPC-157 is almost entirely animal and cell-culture work. Areas that recur across studies include:
- Tendon and ligament models: rodent studies of tendon-to-bone and ligament injury, plus tendon fibroblast cultures examining cell migration and outgrowth.
- Gastrointestinal models: experimental ulcer, fistula and anastomosis models in rats.
- Blood-vessel signaling: work on angiogenesis and the nitric oxide system, often proposed as a common thread behind its effects in other models.
- Muscle and bone models: rodent muscle-crush and fracture-healing studies.
Where the evidence stops
Controlled human clinical data on BPC-157 is very limited, and much of the animal literature comes from a small number of labs. It is not an approved drug in the U.S., and it has been on the World Anti-Doping Agency prohibited list (as a non-approved substance) since 2022. Anyone designing a study should treat it as an early-stage research compound and read the primary papers rather than secondary summaries.
BPC-157 and TB-500
BPC-157 is frequently studied alongside TB-500, a synthetic fragment related to thymosin beta-4, because the two are thought to act through different mechanisms (TB-500 is associated with actin regulation and cell migration). That is the rationale behind combined vials such as our BPC-157 + TB-500 blend and the GLOW and KLOW blends.
Choosing a research vial
- Look for a stated amount per vial (ours: 10mg) and a lyophilized format.
- Store cold and dark; see our guide to lyophilized peptides.
- Review third-party analytical testing before you buy: how to read a COA.
Quick facts
- Full name: Body Protection Compound-157
- Length: 15 amino acids (pentadecapeptide)
- Origin: sequence derived from a gastric juice protein
- Evidence base: mostly rodent and cell-culture studies
Shop the research compounds
Lyophilized vial · $49.99BPC-157 Trio
Buy 2, get 1 free · $99.98BPC-157 + TB-500 Blend
10mg/10mg vial · $99.99BPC-157 + TB-500 Strips
30 count · $179.99
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