Description
Tesamorelin is a synthetic analog of growth hormone-releasing hormone (GHRH), the hypothalamic signal that tells the pituitary gland to release growth hormone. Each vial contains 10mg of lyophilized tesamorelin for laboratory research.
What Is Tesamorelin?
Tesamorelin contains the full 44-amino-acid sequence of human GHRH with a trans-3-hexenoyl group attached at the N-terminus. That modification makes the molecule more resistant to breakdown by dipeptidyl peptidase-4 (DPP-4), the enzyme that rapidly inactivates natural GHRH.
Because it acts upstream at the GHRH receptor, tesamorelin is used to study pulsatile growth hormone release and the downstream IGF-1 response, rather than direct GH exposure. Published research has examined its relationship to lipid and metabolic markers, making it a reference compound in GH-axis research.
Areas of Research Interest
- GHRH receptor signaling and pulsatile GH release
- IGF-1 axis response studies
- Somatotroph and pituitary signaling models
- Lipid-profile and metabolic-marker studies
- Comparative work with shorter GHRH analogs such as CJC-1295 (No DAC)
Product Specifications
- Compound: Tesamorelin (stabilized GHRH 1–44 analog)
- Contents: 10mg per vial
- Form: Lyophilized powder
- Intended use: Laboratory research only
Handling & Storage
Supplied as a lyophilized (freeze-dried) powder in a sealed vial. Store according to the label, protected from heat, light and moisture.
Research History of Tesamorelin
Tesamorelin was developed by Theratechnologies under the research code TH9507. In 2010 the FDA approved a tesamorelin drug product (Egrifta) for a narrow clinical indication, making it the only GHRH analog to reach FDA approval. The 10mg vial sold here is not that drug product. It is a lyophilized research material supplied for laboratory use only.
Published clinical research on tesamorelin has examined visceral adipose tissue in HIV-associated lipodystrophy (Falutz et al., New England Journal of Medicine, 2007), hepatic fat measures (Stanley et al., JAMA, 2014), and cognitive measures in older adults (Baker et al., Archives of Neurology, 2012). These studies are why tesamorelin is a common reference compound in GH-axis and metabolic research models.
Single Tesamorelin 10mg Vial or the Tesamorelin Trio?
A single Tesamorelin 10mg vial is $89.99 and qualifies for free US shipping on its own, since shipping is free on orders over $75. Every order ships within 24 hours.
For longer research timelines, the Tesamorelin Trio bundles three 10mg vials at buy 2, get 1 free pricing. Mixed orders of 3 or more vials also receive 10% off, and 6 or more receive 15% off.
Frequently Asked Questions
What does GHRH(1-44) refer to?
It is the full-length sequence of growth hormone releasing hormone, 44 amino acids long. Tesamorelin is based on that full sequence, in contrast to analogs built on the shorter 1-29 fragment.
Why does DPP-4 resistance matter in research design?
Dipeptidyl peptidase-4 cleaves native GHRH within minutes, which makes controlled exposure difficult to achieve. Resistance to that cleavage extends the window in which receptor engagement can be observed, and is often why Tesamorelin is chosen over native GHRH.
How is tesamorelin different from CJC-1295 (No DAC)?
Tesamorelin keeps the full 44-amino-acid GHRH sequence with an N-terminal modification. CJC-1295 (No DAC) uses only the first 29 amino acids with four substitutions. Both act at the GHRH receptor. See our CJC-1295 + Ipamorelin blend.
Is there a multi-vial option?
Yes. The Tesamorelin Trio bundle includes three 10mg tesamorelin vials for the price of two.
Is Tesamorelin 10mg Vial intended for human use?
No. This product is sold strictly for in vitro and laboratory research by qualified professionals. It is not for human or veterinary use.
How is tesamorelin different from sermorelin?
Sermorelin is GHRH(1-29), the first 29 amino acids of natural GHRH. Tesamorelin keeps the full 44-amino-acid sequence and adds a trans-3-hexenoyl group that resists DPP-4 breakdown. Researchers choose between them based on the sequence length and stability their study design requires.
How should a tesamorelin research vial be stored?
Keep the lyophilized vial sealed, protected from light, and frozen at -20°C for long-term storage. Avoid repeated freeze-thaw cycles. See Handling & Storage above for reconstituted material.
Where does Ageless Peptides ship tesamorelin?
Orders ship within the United States within 24 hours. Shipping is $9.95, or free on orders over $75, which includes a single Tesamorelin 10mg vial.
Related Research Compounds
Sold for research purposes only. Not intended for human consumption. These statements have not been evaluated by the FDA. This product is not a drug, food, or cosmetic and is not intended to diagnose, treat, cure, or prevent any disease.
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